|
Symbol Name ID |
Brca2
breast cancer 2, early onset MGI:109337 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Cerebellar hemorrhage |
Microcephaly |
Aganglionic megacolon |
Anorexia |
Cerebellar calcifications |
Abnormal nervous system morphology |
Abnormal cranial nerve morphology |
Hydrocephalus |
Ventriculomegaly |
Cerebellar cyst |
Spina bifida |
Spinal cord tumor |
Medulloblastoma |
Cerebellar medulloblastoma |
Neuroblastoma |
Ataxia |
Cerebellar ataxia associated with quadrupedal gait |
Dysmetria |
Progressive cerebellar ataxia |
Intention tremor |
Cranial nerve paralysis |
Increased intracranial pressure |
Irritability |
Lethargy |
Cognitive impairment |
Intellectual disability |
Hyperreflexia |
Abnormal brain FDG positron emission tomography |
Headache |
Global developmental delay |
| Disease(s) Associated with BRCA2 | ||||||||||||||||||||||||||||||
| Fanconi anemia | ||||||||||||||||||||||||||||||
| Fanconi anemia complementation group D1 | ||||||||||||||||||||||||||||||
| medulloblastoma | ||||||||||||||||||||||||||||||
| pancreatic cancer |
| Mouse Phenotypes | nervous system phenotype |
open neural tube |
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| Availability | Mouse Genotype | ||
| Brca2tm1Mbn/Brca2tm1Mbn | |||
| Brca2tm1Brn/Brca2tm1Brn Tg(Nes-cre)1Kln/0 (conditional) |
* | ||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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